8th Baltic Congress of Radiology

08.10.2022 Tallinn, Estonia

Possibilities of diagnosis of hepatosteatosis in children

Mare Lintrop (Estonia)

Radiologist and senior teaching physician, Radiology Clinic, Tartu University Hospital

Biography: Qualification: MD, a radiologist with practical experience in general and pediatric radiology, MSc in radiation biology. Academic and research activity include: Imaging of JIA and other MS disorders in children; Radiological imaging of organ damage and evaluation of the development of brain damage after birth asphyxia; Causes and radiological imaging of perinatal stroke; Radiological imaging in inflicted traumatic brain injury in infants.

Presentation

Stalker Hall

Synopsis: Fatty liver is common in children and adolescents affecting approximately with an estimated prevalence of 10%, and is characterized histologically by the accumulation of triglycerides within the hepatocytes. Because of the high prevalence of obesity, there are many children at risk for non-alcoholic fatty liver disease (NAFLD). NAFLD includes a broad range of clinicopathologic features ranging from simple steatosis to steatohepatitis with or without fibrosis, and cirrhosis and is only one of many conditions in which hepatic steatosis is an important histologic component. Hepatic steatosis also can occur in drug-induced liver injury, metabolic diseases (i.e. α-1-antitrypsin deficiency), viral or autoimmune hepatitis, cystic fibrosis, protein malnutrition, and Wilson disease. Furthermore, fatty liver is regarded as a cardiometabolic risk factor. Historically, the diagnosis and management of chronic liver disease, including NAFLD, has relied on liver biopsy. In 2012, however, the European Society for Paediatric Gastroenterology Hepatology and Nutrition (ESPGHAN) assessed that liver biopsy should not be used as a screening procedure in patients with NAFLD. In this setting, diagnostic radiology offers several methods as ultrasound (US), US elastography and MRI, that can provide noninvasive, nonionizing and repeatable imaging and quantitative analyses of liver steatosis. US elastography is now being increasingly used in clinical practice. In recent years, several new US elastography techniques as attenuation imaging (ATI) have been defined to detect liver steatosis. In the presentation, I will discuss our initial experience with the use of ultrasound elastography in the diagnosis of hepatosteatosis in children.

This agenda item is presented in the following session: PCS2-4 Pediatric Radiology - 4th Set

Pre-conference symposium

06.10.2022 15:30 - 17:00