Type of abstract
oral abstract
Objective
To analyse the radiological and clinical features of patients with adrenal tumours in one university center (Hospital of Lithuanian University of Health Sciences, Kauno klinikos) and to try to find any regularities, related to clinical data.
Methods
Medical documentation of 150 patients (53 women and 97 men), who had adrenal tumors diagnosed by CT or/and by MRI, were analysed. Essential clinical and laboratory (hormone assessment) data were documented. Age, height, weight, BMI, systolic and diastolic blood pressure, pulse were recorded together with results of investigation of DHEAS, testosterone, TTH, aldosterone, ACTH, fT4, cortisol, renin, metanefrine, normethanefrine, aldosterone/renin ratio.
Results
Age of women and men at the moment of AT diagnosis was the same (60,9 and 60,5 years respectively). No difference of systolic and diastolic blood pressure, pulse and BMI was detected between women and men.
Concentration of aldosterone (around 70%), ACTH (around 40%), cortisol (around 70%), renin (around 60%) , methanephrine and normethanephrine (around 65%) and aldosterone/renin ratio (around 25%) were investigated with the same frequency both in women and men. TTH, fT4 and DHEAS were assessed more frequently in female, than in male patients (48, 41 and 50% and 32, 28 and 40% respectively). Surprisingly, testosterone was assessed rarely both in women (7%) and men (8,25%). Without hormone investigations remained 5,5 % of women and 20,6% of men.
Unilateral, as well as bilateral, adrenal tumours were detected with the same frequency (64,8% female vs 63,9% male, as well as 11,1% of female vs 16,5% of male patients).
Minor visual changes of adrenals were detected with similar frequency in both genders (3,7% in females and 5,2% in males).
Surgery was performed in 7,4% of female, and in 5,2% of male patients. In female patients all resections were unilateral, in male 3,1% of cases were unilateral.
In case of bilateral AT, unilateral resection was performed more frequently in female, compared to male patients (5,6% vs 2,1%).
Conclusions
TTH, fT4 and DHEAS were assessed more frequently in female, than in male patients. Surprisingly, testosterone was assessed rarely both sexes. Without hormone investigations remained 5,5 % of women and 20,6% of men.
Unilateral, as well as bilateral, adrenal tumours were detected with the same frequency (female vs male patients).
Minor visual changes of adrenals were detected with similar frequency in both genders, as well.
In case of bilateral AT, unilateral resection was performed more frequently in female, compared to male patients
Brief description of the abstract
Adrenal tumors are common a finding. Modern image techniques occupie a central place in the diagnosis of adrenal tumors. After diagnosis of an adrenal tumor, a multidisciplinary team clarifies the diagnosis and prescribes treatment for the patients. This is usually performed in tertiary hospital (university clinic in our case). We attempted to analyse retrospectively, how this system works in real life, and tried to find any regularities, related to clinical data and radiological findings.